Nowy marker udaru niedokrwiennego mózgu

American Neurological Association (ANA) 136th Annual Meeting: October 13, 2011 (San Diego, California) — Increased NR2 peptide levels accurately identify patients with acute ischemic stroke within 24 hours of symptom onset and correlate with neuroimaging findings, results of a pilot study suggest. Dr. Bettermann reported the results here at the American Neurological Association (ANA) 136th Annual Meeting, along with Svetlana Dambinova, PhD, from the Laboratory for Biomarker Research, Kennesaw State University, Georgia. A Damage Indicator The NR2 peptide, a proteolytic breakdown product of the brain-specific N-methyl D-aspartate receptor, is an indicator of damage to the blood–brain barrier that follows an acute cerebral ischemic event. The peptide is rapidly released into the bloodstream during acute brain ischemia. The pilot study involved 50 adults with acute ischemic stroke, confirmed by either head computed tomography scanning or brain magnetic resonance imaging scanning within 24 hours of symptom onset, and 102 age- and sex-matched control patients. The control group consisted of 26 healthy adults; 48 adults with vascular risk factors including diabetes and hypertensio